Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591512 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL11440912 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL10929841 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL30271501 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL16110550 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL2593250 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL11440474 | 1.00 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL5824287 | 0.98 | EPHX1 (0.44) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL28026127 | 0.98 | EPHX1 (0.39) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| Cyanide SCHEMBL27483757 | 0.92 | EPHX1 (0.40) | EPHX1SHBGCYP1A2SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2691413-B1 | MACROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION | NEUROVIVE PHARMACEUTICAL AB (SE) | 2014-12-24 | — | — | EP | disclosed |