Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319702 | 0.90 | SCN9A (0.51) | SCN9A | |
| SCHEMBL16319868 | 0.87 | SCN9A (0.59) | SCN9A | |
| SCHEMBL16319627 | 0.87 | SCN9A (0.49) | SCN9AFLT1FLT4KDR | |
| SCHEMBL16319503 | 0.86 | SCN9A (0.66) | SCN9A | |
| SCHEMBL16319528 | 0.85 | SCN9A (0.59) | SCN9A | |
| SCHEMBL16319620 | 0.84 | SCN9A (0.55) | SCN9A | |
| SCHEMBL16319856 | 0.84 | SCN9A (0.56) | SCN9A | |
| SCHEMBL16319362 | 0.84 | SCN9A (0.53) | SCN9A | |
| SCHEMBL16319623 | 0.82 | SCN9A (0.46) | SCN9A | |
| SCHEMBL16319564 | 0.82 | SCN9A (0.56) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |