Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.66 |
| ▸ | EED | O75530 | 3/20 | 0.66 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.66 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.66 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.66 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503369 | 0.87 | EZH2 (0.72) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10255119 | 0.87 | EZH2 (0.76) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL1695112 | 0.86 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10254671 | 0.85 | EZH2 (0.79) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10254889 | 0.84 | EZH2 (0.66) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10254852 | 0.83 | EZH2 (0.69) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10255280 | 0.81 | EZH2 (0.78) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL12499687 | 0.80 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL14755009 | 0.78 | EZH2 (0.86) | EZH2EEDRBBP4SUZ12RBBP7 | |
| SCHEMBL10256868 | 0.77 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566479-B1 | AZAINDAZOLES | GLAXOSMITHKLINE LLC (US) | 2014-12-24 | — | — | EP | disclosed |