Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.63 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021198 | 0.81 | GRM5 (0.67) | GRM5 | |
| SCHEMBL5021197 | 0.81 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4538746 | 0.81 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4543767 | 0.78 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16319444 | 0.78 | GRM5 (1.00) | GRM5 | |
| SCHEMBL4543775 | 0.78 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16319653 | 0.77 | GRM5 (0.62) | GRM5 | |
| SCHEMBL5021995 | 0.74 | GRM5 (0.64) | GRM5 | |
| SCHEMBL5021738 | 0.73 | GRM5 (0.58) | GRM5 | |
| SCHEMBL5021741 | 0.73 | GRM5 (0.58) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-B1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2014-12-24 | — | — | EP | disclosed |