Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18500350 | 0.97 | MCL1 (0.50) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16321322 | 0.95 | MCL1 (0.48) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL18500373 | 0.94 | MCL1 (0.50) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16320669 | 0.93 | MCL1 (0.48) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16351981 | 0.92 | FFAR1 (0.51) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16320799 | 0.92 | MCL1 (0.52) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16351984 | 0.91 | NPC1 (0.46) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL18625355 | 0.88 | PTGER4 (0.56) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL16341035 | 0.88 | KMT2A (0.52) | MCL1FFAR1NR4A1NR4A2NR4A3 | |
| SCHEMBL19158438 | 0.87 | FFAR1 (0.47) | MCL1FFAR1PPARGPPARDFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| EP-2818531-A1 | Polymerisable compounds and the use thereof in liquid-crystal displays | Merck Patent GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |