Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 19/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.76 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.76 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439342 | 0.86 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL438058 | 0.84 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL439241 | 0.84 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16333100 | 0.83 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16333728 | 0.82 | NOTUM (0.76) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16333353 | 0.80 | NOTUM (0.74) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16339256 | 0.79 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL441103 | 0.78 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16333208 | 0.78 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL439138 | 0.78 | NOTUM (1.00) | NOTUMCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616471-B1 | INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS INC (US) | 2014-12-31 | — | — | EP | disclosed |