⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199062 | 1.00 | — | — | |
| SCHEMBL199063 | 1.00 | — | — | |
| SCHEMBL27685894 | 0.98 | ACE (0.46) | — | |
| Hydrochloric Acid SCHEMBL28366660 | 0.98 | ACE (0.46) | — | |
| SCHEMBL27685893 | 0.98 | ACE (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL27857098 | 0.98 | ACE (0.46) | — | |
| Hydrochloric Acid SCHEMBL28366662 | 0.98 | ACE (0.46) | — | |
| SCHEMBL2399501 | 0.93 | ACE (0.42) | — | |
| SCHEMBL4951219 | 0.85 | — | — | |
| SCHEMBL29951832 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-111057736-B | Application of lipase in splitting BOC-DL-proline methyl ester | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| US-8778996-B2 | Method of treating a human being for a class of neurological defects and seizure disorders | CHEMGENES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-8389577-B2 | Method of treating a human being for a class of metabolic defects and energy production disorders | CHEMGENES CORPORATION | 2013-03-05 | — | — | US | disclosed |
| US-20110166230-A1 | Method of treating a human being for a class of neurological defects and seizure disorders | SRIVASTAVA SURESH C | 2011-07-07 | — | — | US | disclosed |
| US-20110166231-A1 | Method of treating a human being for a class of metabolic defects and energy production disorders | CHEMGENES CORPORATION | 2011-07-07 | — | — | US | disclosed |
| US-7932287-B2 | Therapeutic compositions and uses | CHEMGENES CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| EP-1513871-B1 | PYRROLIDINYL PEPTIDE NUCLEIC ACIDS | ISIS INNOVATION (GB) | 2008-10-29 | — | — | EP | disclosed |
| US-7098321-B2 | Homologous peptide nucleic acids | ISIS INNOVATION LIMITED (GB) | 2006-08-29 | — | — | US | disclosed |
| US-20060035972-A1 | Therapeutic compositions and uses | CHEMGENES CORPORATION | 2006-02-16 | — | — | US | disclosed |
| US-20030228588-A1 | Homologous peptide nucleic acids | ISIS INNOVATION LIMITED | 2003-12-11 | — | — | US | disclosed |
| US-20030157500-A1 | Pyrrolidinyl peptide nucleic acids | ISIS INNOVATION LIMITED (GB) | 2003-08-21 | — | — | US | disclosed |
| EP-0308983-A2 | NMR imaging with Mn(II) coordination compositions | SALUTAR, INC. (US) | 1989-03-29 | — | — | EP | disclosed |