Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16337645 | 1.00 | BTK (0.50) | BTKPRMT5EGFRSRC | |
| SCHEMBL15756453 | 0.90 | BTK (0.57) | BTKEGFRSRC | |
| SCHEMBL15756452 | 0.90 | BTK (0.57) | BTKEGFRSRC | |
| SCHEMBL16336970 | 0.90 | BTK (0.54) | BTKEGFRSRC | |
| SCHEMBL16338226 | 0.88 | BTK (0.60) | BTKEGFRSRC | |
| SCHEMBL16338225 | 0.88 | BTK (0.60) | BTKEGFRSRC | |
| SCHEMBL28503533 | 0.85 | BTK (0.56) | BTKEGFRSRC | |
| SCHEMBL28503534 | 0.85 | BTK (0.56) | BTKEGFRSRC | |
| SCHEMBL17157098 | 0.84 | BTK (0.44) | BTKEGFRSRC | |
| SCHEMBL16078935 | 0.84 | BTK (0.56) | BTKEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150005277-A1 | Protein Kinase Inhibitors and Uses Thereof | BEIGENE, LTD. (KY) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005277-A1 | Protein Kinase Inhibitors and Uses Thereof | BTK, ABL1, PRKACA | BTK 1/4885PRMT5 895/4885EGFR 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.