⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345878 | 0.88 | TSHR (0.39) | — | |
| SCHEMBL10787504 | 0.79 | — | — | |
| SCHEMBL9910619 | 0.76 | TDP1 (0.36) | — | |
| SCHEMBL40260 | 0.75 | — | — | |
| Silver SCHEMBL1860970 | 0.74 | — | — | |
| SCHEMBL8815215 | 0.73 | — | — | |
| SCHEMBL549356 | 0.73 | — | — | |
| SCHEMBL20898290 | 0.73 | — | — | |
| SCHEMBL8815223 | 0.73 | — | — | |
| SCHEMBL29260341 | 0.72 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650382-B2 | Heteroarylamide derivatives having antiandrogenic properties | ARANDA PHARMA LTD (FI) | 2017-05-16 | — | — | US | disclosed |
| US-20150005308-A1 | NOVEL HETEROARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | ARANDA PHARMA LTD (FI) | 2015-01-01 | — | — | US | disclosed |