Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16983116 | 0.81 | KCNH2 (0.50) | KCNH2LRRK2PDK2CYP3A4CYP2C9 | |
| SCHEMBL21741529 | 0.79 | KCNH2 (0.47) | KCNH2LRRK2PDK2CYP3A4CYP2C9 | |
| SCHEMBL17661861 | 0.77 | KCNH2 (0.45) | KCNH2LRRK2PDK2CYP3A4CYP2C9 | |
| SCHEMBL1094641 | 0.77 | CA1 (0.44) | IDO1CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL16348325 | 0.76 | KCNH2 (0.42) | KCNH2LRRK2CYP3A4CYP2C9LMNA | |
| SCHEMBL16911361 | 0.73 | PIK3CD (0.49) | KCNH2LRRK2KDM4ELMNAALDH1A1 | |
| SCHEMBL31048769 | 0.72 | KCNH2 (0.38) | IDO1KCNH2LRRK2KDM4ELMNA | |
| SCHEMBL13523181 | 0.72 | IDO1 (0.44) | IDO1CYP2C9KDM4ELMNAALDH1A1 | |
| SCHEMBL16348425 | 0.71 | PPARA (0.51) | KDM4ELMNAALDH1A1MAPTPKM | |
| SCHEMBL23205631 | 0.70 | SMARCA2 (0.71) | LRRK2PDK2KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |