Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 13/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615357 | 0.89 | PRKCQ (0.51) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL11511885 | 0.81 | DAO (0.58) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL30257859 | 0.79 | DAO (0.55) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL30377628 | 0.77 | DAO (0.50) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL30615567 | 0.77 | DAO (0.47) | DAOPRKCQPRKCAADORA3GRIN1 | |
| SCHEMBL30615537 | 0.77 | PRKCQ (0.48) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL21464054 | 0.77 | PRKCQ (0.48) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL30615338 | 0.77 | PRKCQ (0.48) | DAOPRKCQPRKCAALDH1A1GRIN1 | |
| SCHEMBL30794441 | 0.77 | DAO (0.53) | DAOPRKCQPRKCAADORA3ALDH1A1 | |
| SCHEMBL21463768 | 0.76 | PRKCQ (0.50) | DAOPRKCQPRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220735-B2 | Benzimidazolone histamine H3 antagonists | SCHERING CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |