SCHEMBL16348778

SCHEMBL16348778

CN1c2ccccc2C(C)(C)C12C=Cc1cccc(OC(=O)O)c1O2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.52
GAA P10253 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
LMNA P02545 4/20 0.52
NPSR1 Q6W5P4 3/20 0.52
RECQL P46063 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
ALOX15 P16050 2/20 0.52
ALPG P10696 1/20 0.52
TP53 P04637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
GFER P55789 1/20 0.41
THRB P10828 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
PKM P14618 2/20 0.39
PLIN1 O60240 1/20 0.39
TSHR P16473 1/20 0.39
PLIN5 Q00G26 1/20 0.39
ABHD5 Q8WTS1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16312899 0.87 MAPT (0.48) MAPTGAAMEN1KMT2ALMNA
SCHEMBL29532854 0.85 MAPT (0.54) MAPTGAAMEN1KMT2ALMNA
SCHEMBL6102948 0.85 MAPT (0.54) MAPTGAAMEN1KMT2ALMNA
SCHEMBL16363801 0.84 MAPT (0.50) MAPTGAAMEN1KMT2ALMNA
SCHEMBL7068427 0.84 MAPT (0.55) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8682635 0.83 MAPT (0.51) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8681138 0.82 MAPT (0.57) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680534 0.81 MAPT (0.52) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680295 0.81 MAPT (0.62) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680325 0.78 MAPT (0.56) MAPTGAAMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed