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SCHEMBL16349151

SCHEMBL16349151

C[C@H]1OC(C2CCCC2)OC(N2C=C3C=C(c4ccc5ccccc5c4)OC3NC2=O)O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 1/20 0.31
▸ P2RY6 Q15077 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13614934 0.89 P2RY12 (0.34) P2RY2P2RY6
SCHEMBL13614583 0.89 P2RY12 (0.34) P2RY2P2RY6
SCHEMBL13614516 0.81 P2RY12 (0.35) P2RY2P2RY6
SCHEMBL14017341 0.81 P2RY12 (0.35) P2RY2P2RY6
SCHEMBL13614498 0.76 P2RY2 (0.42) P2RY2P2RY6
SCHEMBL14017300 0.76 P2RY2 (0.42) P2RY2P2RY6
SCHEMBL16326152 0.74 — —
SCHEMBL16349152 0.70 P2RY12 (0.37) P2RY2P2RY6
SCHEMBL13614550 0.70 P2RY2 (0.41) P2RY2P2RY6
SCHEMBL13614888 0.70 P2RY2 (0.41) P2RY2P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612047-B2 Degradation-resistant mononucleoside phosphate compounds INSPIRE PHARMACEUTICALS, INC. (US) 2009-11-03 — — US disclosed