SCHEMBL16350076

SCHEMBL16350076

COC(=O)c1cc(C)c2ccccc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.50
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 5/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
PADI4 Q9UM07 1/20 0.47
NR4A2 P43354 3/20 0.46
HPGD P15428 2/20 0.46
CREBBP Q92793 1/20 0.46
POLB P06746 2/20 0.46
NSD2 O96028 1/20 0.46
MCL1 Q07820 1/20 0.46
HSD17B10 Q99714 2/20 0.44
CFTR P13569 1/20 0.44
BRD4 O60885 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1791233 0.84 KDM4E (0.66) MAPTMEN1KMT2ALMNATSHR
SCHEMBL11066829 0.82 HPGD (0.51) MAPTMEN1KMT2ALMNATSHR
SCHEMBL485382 0.81 KMT2A (0.50) MAPTMEN1KMT2ALMNATSHR
SCHEMBL17240274 0.81 MAPT (0.50) MAPTMEN1KMT2ALMNATSHR
SCHEMBL31300298 0.81 KDM4E (0.65) MAPTMEN1KMT2ALMNATSHR
SCHEMBL9091761 0.81 MEN1 (0.50) MAPTMEN1KMT2ALMNATSHR
SCHEMBL13401400 0.81 KDM4E (0.65) MAPTMEN1KMT2ALMNATSHR
SCHEMBL27707703 0.80 MAPT (0.70) MAPTMEN1KMT2ALMNATSHR
SCHEMBL10343413 0.80 HSD17B10 (0.67) MAPTMEN1KMT2ALMNATSHR
SCHEMBL6824108 0.77 MEN1 (0.63) MAPTMEN1KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 US disclosed