SCHEMBL16355165

SCHEMBL16355165

O=[N+]([O-])c1ccccc1[N+](=O)[O-].O=[N+]([O-])c1ccccc1[N+](=O)[O-]

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 5/20 0.65
GPR35 Q9HC97 2/20 0.62
ALDH1A1 P00352 8/20 0.61
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
TSHR P16473 3/20 0.58
NPC1 O15118 1/20 0.56
RECQL P46063 1/20 0.56
RAB9A P51151 1/20 0.56
LMNA P02545 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
MAPK1 P28482 1/20 0.54
CASP7 P55210 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
S100A4 P26447 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22566 1.00 HSD17B10 (0.67) HSD17B10TDP1GPR35ALDH1A1KMT2A
SCHEMBL29577518 1.00 HSD17B10 (0.67) HSD17B10TDP1GPR35ALDH1A1KMT2A
Hydrogen Sulfide SCHEMBL28883138 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
SCHEMBL6553154 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
Water SCHEMBL27294136 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
SCHEMBL6553157 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
Fluoride SCHEMBL11797732 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
SCHEMBL6553158 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
Ammonia Solution, Strong SCHEMBL11649737 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A
Fluoride SCHEMBL27513971 0.97 HSD17B10 (0.64) HSD17B10TDP1GPR35ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473477-B1 PROCESS FOR PREPARING MONONITRATED ORGANIC COMPOUNDS BASF SE (DE) 2015-01-14 EP disclosed
CN-102942485-B Method for m-dinitrobenzene refinement and effective byproduct utilization ZHEJIANG LONGSHENG CHEMICAL RES CO LTD 2014-12-10 CN disclosed
CN-102942485-A Method for m-dinitrobenzene refinement and effective byproduct utilization ZHEJIANG LONGSHENG CHEMICAL RES CO LTD 2013-02-27 CN disclosed
CN-1078885-C Process for nitrating diphenyl ether compound ZENECA LTD (GB) 2002-02-06 CN disclosed
CN-1196045-A Process for nitrating diphenyl ether compounds ZENECA LTD (GB) 1998-10-14 CN disclosed