Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15432739 | 0.99 | SLC34A2 (0.60) | SLC34A2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL16355213 | 0.91 | SLC34A2 (0.62) | SLC34A2BRAFRAF1HTR2AHTR2C | |
| SCHEMBL16355209 | 0.91 | SLC34A2 (0.62) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL15432757 | 0.90 | SLC34A2 (0.64) | SLC34A2BRAFRAF1HTR2AHTR2C | |
| SCHEMBL15432752 | 0.90 | SLC34A2 (0.63) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL15420892 | 0.90 | SLC34A2 (0.56) | SLC34A2DRD2BRAFRAF1HTR2A | |
| SCHEMBL15432736 | 0.88 | SLC34A2 (0.75) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL19580025 | 0.88 | SLC34A2 (0.75) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL46437 | 0.88 | SLC34A2 (0.60) | SLC34A2BRAFRAF1ROCK2ROCK1 | |
| SCHEMBL16355211 | 0.88 | SLC34A2 (0.64) | SLC34A2BRAFRAF1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8916569-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2014-12-23 | — | — | US | disclosed |