Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 8/20 | 0.41 |
| ▸ | RAF1 | P04049 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15420838 | 0.99 | SLC34A2 (0.60) | SLC34A2BRAFRAF1HTR2AKCNH2 | |
| SCHEMBL39828 | 0.94 | SLC34A2 (0.52) | SLC34A2BRAFRAF1HTR2AKCNH2 | |
| SCHEMBL16355209 | 0.91 | SLC34A2 (0.62) | SLC34A2BRAFRAF1 | |
| SCHEMBL16355210 | 0.91 | SLC34A2 (0.60) | SLC34A2BRAFRAF1HTR2AKCNH2 | |
| SCHEMBL16355207 | 0.90 | SLC34A2 (0.65) | SLC34A2BRAFRAF1 | |
| SCHEMBL15432752 | 0.90 | SLC34A2 (0.63) | SLC34A2BRAFRAF1 | |
| SCHEMBL16355215 | 0.90 | SLC34A2 (0.70) | SLC34A2BRAFRAF1KCNH2 | |
| SCHEMBL15432766 | 0.90 | SLC34A2 (0.70) | SLC34A2BRAFRAF1KCNH2 | |
| SCHEMBL15432751 | 0.90 | SLC34A2 (0.65) | SLC34A2BRAFRAF1 | |
| SCHEMBL15432747 | 0.90 | SLC34A2 (0.61) | SLC34A2BRAFRAF1HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916569-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2014-12-23 | — | — | US | disclosed |