SCHEMBL16356282

SCHEMBL16356282

CCCCN1C(=O)c2cscc2C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.42
PTGS2 P35354 3/20 0.42
MGLL Q99685 2/20 0.42
FAAH O00519 1/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
RGS12 O14924 2/20 0.42
HTT P42858 2/20 0.42
KMT2A Q03164 2/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TLR9 Q9NR96 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 3/20 0.41
ALDH2 P05091 1/20 0.41
ALDH3A1 P30838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14881088 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL15929294 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL14881169 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL15929367 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL16356272 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL2031441 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL1690112 0.92 PTGS1 (0.53) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL12601339 0.88 MEN1 (0.39) MEN1KMT2AMAPK1L3MBTL1ALDH1A1
SCHEMBL17412780 0.84 PTGS1 (0.45) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL16356278 0.80 MAPT (0.41) MAPTALDH1A1TERTSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9508936-B2 Organic semiconductor material E.T.C. S.R.L. (IT) 2016-11-29 US disclosed
US-9508936-B2 Organic semiconductor material E.T.C. S.R.L. (IT) 2016-11-29 US disclosed
US-9412950-B2 Polymer compound and organic photoelectric conversion device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-9412950-B2 Polymer compound and organic photoelectric conversion device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
EP-3048156-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
EP-3048155-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2016-07-27 EP disclosed
EP-2768835-B1 5H-THIENO[2,3-c]PYRROLE-4,6-DIONE BASED ORGANIC SEMICONDUCTOR MATERIAL E T C SRL (IT) 2016-04-27 EP disclosed
US-20150214488-A1 ORGANIC SEMICONDUCTOR MATERIAL USINVEST LLC 2015-07-30 US disclosed
US-20150214488-A1 ORGANIC SEMICONDUCTOR MATERIAL USINVEST LLC 2015-07-30 US disclosed
US-20140373912-A1 POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-25 US disclosed
US-20140373912-A1 POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-25 US disclosed
WO-2014057422-A1 ORGANIC SEMICONDUCTOR MATERIAL E.T.C. S.R.L. (IT) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150214488-A1 ORGANIC SEMICONDUCTOR MATERIAL OR10J3, OR51E2, MSI2 PTGS1 4225/4885PTGS2 4194/4885MGLL 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.