SCHEMBL16358277

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](O)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)O)[C@H](O)C(N)=O)[C@H](C)O

nearest known ligand 0.44

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	16/20	0.44

▸	PSEN2	P49810	16/20	0.44

▸	APH1B	Q8WW43	16/20	0.44

▸	NCSTN	Q92542	16/20	0.44

▸	APH1A	Q96BI3	16/20	0.44

▸	PSENEN	Q9NZ42	16/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12293279	1.00	PSEN1 (0.44)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13323741	1.00	PSEN1 (0.44)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13724103	0.97	PSEN1 (0.45)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13724091	0.95	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13724406	0.94	PSEN1 (0.44)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13722825	0.94	PSEN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13723416	0.93	VIPR1 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13723626	0.93	PSEN1 (0.42)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4088608	0.91	PSEN1 (0.42)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13724260	0.90	PSEN1 (0.46)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007118691-A1	LYSOBACTIN AMIDES	AICURIS GMBH & CO. KG (DE)	2007-10-25	—	—	WO	disclosed