Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664154 | 0.98 | SGPL1 (0.44) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL13637149 | 0.98 | SGPL1 (0.44) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL14848265 | 0.98 | SGPL1 (0.44) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL16180731 | 0.98 | SGPL1 (0.40) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL13827706 | 0.93 | SGPL1 (0.41) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL15368891 | 0.93 | SGPL1 (0.41) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL27472493 | 0.89 | SGPL1 (0.41) | SGPL1DNM1CA2FDPSLMNA | |
| SCHEMBL23038325 | 0.88 | SGPL1 (0.33) | SGPL1DNM1CA2FDPS | |
| SCHEMBL13784736 | 0.88 | SGPL1 (0.42) | SGPL1CA2FDPSLMNATSHR | |
| SCHEMBL23038570 | 0.86 | SGPL1 (0.39) | SGPL1DNM1CA2FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021947-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |