Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12791521 | 0.93 | KMT2A (0.62) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL2055295 | 0.93 | KMT2A (0.62) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL2055303 | 0.93 | KMT2A (0.62) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL2055299 | 0.93 | KMT2A (0.62) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL64783 | 0.91 | KMT2A (0.65) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL24304867 | 0.88 | TSHR (0.61) | TSHRKMT2AMEN1PHF8KDM2A | |
| SCHEMBL25496716 | 0.87 | MEN1 (0.58) | TSHRKMT2AMEN1PHF8KDM5C | |
| SCHEMBL12450195 | 0.86 | KMT2A (0.56) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL2055304 | 0.86 | KMT2A (0.56) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL12119572 | 0.86 | TSHR (0.59) | TSHRKMT2AMEN1PHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076242-A1 | AMIDO-AMINE POLYMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |