Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849239 | 0.92 | PTH1R (0.50) | PTH1RTACR1IDH1TRPV4 | |
| SCHEMBL849248 | 0.86 | PTH1R (0.47) | PTH1RTACR1 | |
| SCHEMBL849249 | 0.86 | PTH1R (0.47) | PTH1RTACR1 | |
| SCHEMBL847032 | 0.85 | PTH1R (0.63) | PTH1RIDH1TRPV4 | |
| SCHEMBL846998 | 0.84 | PTH1R (0.41) | PTH1RTACR1TRPV4 | |
| SCHEMBL850320 | 0.84 | PTH1R (0.52) | PTH1RTACR1 | |
| SCHEMBL850075 | 0.82 | PTH1R (0.51) | PTH1RIDH1TRPV4 | |
| SCHEMBL850074 | 0.82 | PTH1R (0.51) | PTH1RIDH1TRPV4 | |
| SCHEMBL849516 | 0.82 | PTH1R (0.52) | PTH1RMMP2 | |
| SCHEMBL13552118 | 0.81 | PTH1R (0.47) | PTH1RTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |