SCHEMBL16358587

SCHEMBL16358587

CCCCCCCCCC1=NC2(CCN([S+]([O-])CCc3c(C)cc(N(C)C(N)=O)cc3C)CC2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17215267 1.00 PTH1R (0.47) PTH1R
SCHEMBL16104848 1.00 PTH1R (0.47) PTH1R
SCHEMBL16358359 0.94 PTH1R (0.46) PTH1R
SCHEMBL16358811 0.94 PTH1R (0.46) PTH1R
SCHEMBL16358624 0.92 PTH1R (0.44) PTH1R
SCHEMBL16358770 0.91 PTH1R (0.44) PTH1R
SCHEMBL16358749 0.89 PTH1R (0.45) PTH1R
SCHEMBL16358739 0.86 PTH1R (0.33) PTH1R
SCHEMBL847337 0.83 PTH1R (0.67) PTH1R
SCHEMBL849845 0.83 PTH1R (0.67) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed