Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849400 | 0.93 | PTH1R (0.53) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL13553382 | 0.93 | PTH1R (0.53) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL13064696 | 0.84 | PTH1R (0.53) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL849146 | 0.84 | PTH1R (0.53) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL13553380 | 0.81 | PTH1R (0.58) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL851294 | 0.81 | PTH1R (0.58) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL13553376 | 0.79 | PTH1R (0.58) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL848923 | 0.79 | PTH1R (0.58) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL13553381 | 0.79 | PTH1R (0.58) | PTH1RADAMTS4ADAMTS5 | |
| SCHEMBL17437740 | 0.79 | PTH1R (0.51) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |