SCHEMBL16358607

SCHEMBL16358607

Cc1cc(C(C)(C)C)cc(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(C1CCC(C)CC1)NC2=O

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 12/20 0.73
NEK2 P51955 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL879739 0.90 PTH1R (0.76) PTH1R
Hydrochloric Acid SCHEMBL850194 0.89 PTH1R (0.75) PTH1R
SCHEMBL16359053 0.89 PTH1R (0.70) PTH1R
SCHEMBL879802 0.88 PTH1R (0.72) PTH1R
SCHEMBL848725 0.88 PTH1R (0.72) PTH1R
SCHEMBL16358677 0.88 PTH1R (0.73) PTH1R
SCHEMBL16302412 0.85 PTH1R (0.77) PTH1R
SCHEMBL849620 0.85 PTH1R (0.70) PTH1R
SCHEMBL849859 0.85 PTH1R (0.77) PTH1R
SCHEMBL850192 0.85 PTH1R (0.78) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed