SCHEMBL16358656

SCHEMBL16358656

CC(C)c1nc2c(c3c1[C@@H](c1ccc(C(F)(F)F)cc1)OC31CCOCC1)C(O[Si](C)(C)C(C)(C)C)CC1(CC1)C2

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15182795 1.00 CETP (0.74) CETP
SCHEMBL15182797 1.00 CETP (0.74) CETP
SCHEMBL16358963 1.00 CETP (0.74) CETP
SCHEMBL664739 0.97 CETP (0.69) CETP
SCHEMBL16258440 0.97 CETP (0.69) CETP
SCHEMBL14312066 0.97 CETP (0.69) CETP
SCHEMBL664512 0.97 CETP (0.69) CETP
SCHEMBL663086 0.97 CETP (0.69) CETP
SCHEMBL16258432 0.93 CETP (0.73) CETP
SCHEMBL16258458 0.93 CETP (0.73) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013024130-A1 FURO[3,4-C]QUINOLINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-21 WO disclosed