Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.78 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848077 | 0.95 | PTH1R (0.80) | PTH1RCALCRLADAMTS4ADAMTS5TRPV1 | |
| SCHEMBL879961 | 0.95 | PTH1R (0.80) | PTH1RCALCRLADAMTS4ADAMTS5TRPV1 | |
| SCHEMBL13555100 | 0.94 | PTH1R (0.77) | PTH1RCALCRLADAMTS4ADAMTS5TRPV1 | |
| SCHEMBL13064860 | 0.94 | PTH1R (0.77) | PTH1RCALCRLADAMTS4ADAMTS5TRPV1 | |
| SCHEMBL847860 | 0.94 | PTH1R (0.77) | PTH1RCALCRLADAMTS4ADAMTS5TRPV1 | |
| SCHEMBL13555167 | 0.92 | PTH1R (0.82) | PTH1RCALCRLADAMTS4ADAMTS5MMP2 | |
| SCHEMBL13555152 | 0.92 | PTH1R (0.82) | PTH1RCALCRLADAMTS4ADAMTS5MMP2 | |
| SCHEMBL849537 | 0.92 | PTH1R (0.82) | PTH1RCALCRLADAMTS4ADAMTS5MMP2 | |
| SCHEMBL848053 | 0.91 | PTH1R (0.81) | PTH1RCALCRLTRPV1 | |
| SCHEMBL847792 | 0.91 | PTH1R (0.82) | PTH1RCALCRLTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |