Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.71 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850346 | 0.91 | PTH1R (0.67) | PTH1R | |
| SCHEMBL850073 | 0.90 | PTH1R (0.69) | PTH1RSLC6A9CALCRL | |
| SCHEMBL847587 | 0.86 | PTH1R (0.56) | PTH1R | |
| SCHEMBL849189 | 0.83 | PTH1R (1.00) | PTH1RSLC6A9CALCRL | |
| SCHEMBL880039 | 0.83 | PTH1R (0.81) | PTH1RSLC6A9CALCRL | |
| SCHEMBL16358763 | 0.83 | PTH1R (0.49) | PTH1RCALCRL | |
| SCHEMBL16302561 | 0.83 | PTH1R (0.70) | PTH1R | |
| SCHEMBL849957 | 0.82 | PTH1R (1.00) | PTH1RSLC6A9CALCRL | |
| SCHEMBL16358562 | 0.81 | PTH1R (0.81) | PTH1RCALCRL | |
| SCHEMBL850199 | 0.81 | PTH1R (0.67) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |