SCHEMBL16358795

SCHEMBL16358795

Cc1cc(C(=O)N(C)C)ccc1CCSN1CCC2(CC1)N=C(COc1ccc(F)c(F)c1F)NC2=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 6/20 0.34
PTGER1 P34995 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846973 0.86 PTH1R (0.43) MAPK14
SCHEMBL849941 0.75 PTH1R (0.43)
SCHEMBL848174 0.73 PTH1R (0.45) MAPK14
SCHEMBL848316 0.72 PTH1R (0.45)
SCHEMBL848984 0.67 PTH1R (0.49)
SCHEMBL13551831 0.66 PTH1R (0.47)
SCHEMBL849582 0.66 PTH1R (0.48)
SCHEMBL849559 0.66 PTH1R (0.48)
SCHEMBL848705 0.66 PTH1R (0.46)
SCHEMBL849387 0.65 PTH1R (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed