Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849946 | 0.89 | PTH1R (0.42) | PTH1R | |
| SCHEMBL16302172 | 0.86 | PTH1R (0.40) | PTH1RHPGDS1PR1 | |
| SCHEMBL16357936 | 0.83 | PTH1R (0.46) | PTH1R | |
| SCHEMBL13386014 | 0.82 | PTH1R (0.41) | PTH1R | |
| SCHEMBL850389 | 0.81 | PTH1R (0.46) | PTH1R | |
| SCHEMBL850388 | 0.81 | PTH1R (0.46) | PTH1R | |
| SCHEMBL847225 | 0.81 | PTH1R (0.41) | PTH1RHPGD | |
| SCHEMBL847226 | 0.81 | PTH1R (0.41) | PTH1RHPGD | |
| SCHEMBL18211326 | 0.80 | PTH1R (0.51) | PTH1R | |
| Cyclopropane SCHEMBL16087525 | 0.80 | PTH1R (0.51) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |