Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NMT2 | O60551 | 2/20 | 0.42 |
| ▸ | NMT1 | P30419 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329426 | 0.97 | TLR2 (0.43) | TLR2EPHX2NMT2NMT1NPY4R | |
| SCHEMBL10169928 | 0.93 | OPRL1 (0.40) | TLR2EPHX2NMT2NMT1NPY4R | |
| SCHEMBL22930530 | 0.90 | EPHX2 (0.52) | TLR2EPHX2NMT2NMT1NPY4R | |
| SCHEMBL4940275 | 0.90 | EPHX2 (0.52) | TLR2EPHX2NMT2NMT1NPY4R | |
| SCHEMBL29536066 | 0.89 | GNPAT (0.50) | NMT2NMT1NPY4RNPY5RNPY1R | |
| SCHEMBL14193566 | 0.89 | GNPAT (0.40) | NMT2NMT1NPY4RNPY5RNPY1R | |
| SCHEMBL15314079 | 0.88 | NPY4R (0.37) | TLR2EPHX2NMT2NMT1NPY4R | |
| SCHEMBL17440322 | 0.88 | QRFPR (0.42) | TLR2NMT2NMT1NPY4RNPY5R | |
| SCHEMBL13319653 | 0.88 | QRFPR (0.42) | TLR2NMT2NMT1NPY4RNPY5R | |
| SCHEMBL5849482 | 0.87 | OPRL1 (0.40) | NPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134761-A2 | MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | WO | disclosed |