SCHEMBL16359072

SCHEMBL16359072

CNc1cc(C)c(/C=C/S(=O)(=O)N2CCC3(CC2)N=C(CCCCCCCC(C)(F)F)NC3=O)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 8/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL849631 0.94 PTH1R (0.34) PTH1R
SCHEMBL849630 0.94 PTH1R (0.34) PTH1R
SCHEMBL848088 0.93 PTH1R (0.33) PTH1R
SCHEMBL848087 0.93 PTH1R (0.33) PTH1R
SCHEMBL13552769 0.89 PTH1R (0.35) PTH1R
SCHEMBL850309 0.88 PTH1R (0.36) PTH1R
SCHEMBL850583 0.88 PTH1R (0.36) PTH1R
SCHEMBL850310 0.88 PTH1R (0.36) PTH1R
SCHEMBL16358694 0.88 PTH1R (0.35) PTH1R
SCHEMBL850582 0.88 PTH1R (0.36) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed