SCHEMBL16359148

SCHEMBL16359148

Cc1cc(NC(=O)OC(C)(C)C)c(O)c(C)c1CC[S+]([O-])N1CCC2(CC1)N=C(C1CCC(C)CC1)NC2=O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL848641 0.85 PTH1R (0.60) PTH1R
SCHEMBL16358580 0.79 PTH1R (0.52) PTH1R
SCHEMBL16302414 0.78 PTH1R (0.47) PTH1R
SCHEMBL16359021 0.75 PTH1R (0.54) PTH1R
SCHEMBL16358074 0.74 PTH1R (0.71) PTH1R
SCHEMBL16359063 0.73 PTH1R (0.63) PTH1R
SCHEMBL16302389 0.71 PTH1R (0.52) PTH1R
SCHEMBL16358617 0.71 PTH1R (0.42) PTH1R
SCHEMBL16104667 0.71 PTH1R (0.47) PTH1R
SCHEMBL16302384 0.71 PTH1R (0.50) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed