Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848132 | 0.92 | PTH1R (0.49) | PTH1RMGLL | |
| SCHEMBL848131 | 0.92 | PTH1R (0.49) | PTH1RMGLL | |
| SCHEMBL16359191 | 0.90 | PTH1R (0.42) | PTH1RALDH1A1RECQL | |
| SCHEMBL848787 | 0.88 | PTH1R (0.41) | PTH1R | |
| SCHEMBL848788 | 0.88 | PTH1R (0.41) | PTH1R | |
| SCHEMBL16358809 | 0.88 | PTH1R (0.54) | PTH1R | |
| SCHEMBL16358808 | 0.86 | PTH1R (0.46) | PTH1R | |
| SCHEMBL849349 | 0.84 | PTH1R (0.46) | PTH1RMGLL | |
| SCHEMBL849348 | 0.84 | PTH1R (0.46) | PTH1RMGLL | |
| SCHEMBL16302216 | 0.84 | PTH1R (0.37) | PTH1RALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |