Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848039 | 0.94 | PTH1R (0.41) | PTH1RKDRPDGFRBCNR2JAK2 | |
| SCHEMBL848040 | 0.94 | PTH1R (0.41) | PTH1RKDRPDGFRBCNR2JAK2 | |
| SCHEMBL16302498 | 0.90 | PTH1R (0.37) | PTH1R | |
| SCHEMBL849625 | 0.90 | PTH1R (0.37) | PTH1RKDRPDGFRBCNR2JAK2 | |
| SCHEMBL849624 | 0.90 | PTH1R (0.37) | PTH1RKDRPDGFRBCNR2JAK2 | |
| SCHEMBL849018 | 0.89 | PTH1R (0.36) | PTH1RKDRPDGFRB | |
| SCHEMBL849017 | 0.89 | PTH1R (0.36) | PTH1RKDRPDGFRB | |
| SCHEMBL16302547 | 0.88 | PTH1R (0.35) | PTH1RKDRPDGFRBCNR2 | |
| SCHEMBL848576 | 0.87 | PTH1R (0.42) | PTH1R | |
| SCHEMBL848575 | 0.87 | PTH1R (0.42) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |