Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 13/20 | 0.46 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664688 | 1.00 | CETP (0.46) | CETPPDE2APDE10A | |
| SCHEMBL16360035 | 0.91 | CETP (0.52) | CETP | |
| SCHEMBL664625 | 0.91 | CETP (0.52) | CETP | |
| SCHEMBL665918 | 0.90 | CETP (0.58) | CETP | |
| SCHEMBL663063 | 0.90 | CETP (0.58) | CETP | |
| SCHEMBL16360303 | 0.90 | CETP (0.58) | CETP | |
| SCHEMBL16360582 | 0.90 | CETP (0.58) | CETP | |
| SCHEMBL16258321 | 0.90 | CETP (0.58) | CETP | |
| SCHEMBL16258288 | 0.88 | CETP (0.45) | CETP | |
| SCHEMBL665277 | 0.88 | CETP (0.45) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101424-A1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-25 | — | — | WO | disclosed |