SCHEMBL16360371

SCHEMBL16360371

COc1ccc(C(OC[C@@H](OC)[C@@H](O)CCn2cnc3c(=O)[nH]c(NC(=O)C(C)C)nc32)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.39
TK1 P04183 2/20 0.38
PDE9A O76083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27041198 0.87 HPRT1 (0.40) TYMPTK1PDE9A
SCHEMBL27041175 0.87 HPRT1 (0.40) TYMPTK1PDE9A
SCHEMBL27041171 0.87 HPRT1 (0.40) TYMPTK1PDE9A
SCHEMBL31273672 0.84 KDM4E (0.39) TYMPTK1PDE9A
SCHEMBL31273452 0.81 TYMP (0.38) TYMPTK1PDE9A
SCHEMBL31273886 0.80 TYMP (0.36) TYMPTK1PDE9A
SCHEMBL18490399 0.76 TYMP (0.48) TYMPPDE9A
SCHEMBL14955126 0.76 MEN1 (0.49) TYMPTK1
SCHEMBL18490366 0.76 TYMP (0.47) TYMPPDE9A
SCHEMBL18490263 0.76 TYMP (0.47) TYMPPDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed