Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 7/20 | 0.60 |
| ▸ | CHRND | Q07001 | 5/20 | 0.59 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.59 |
| ▸ | CHRNG | P07510 | 1/20 | 0.59 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299950 | 1.00 | GRIA1 (0.60) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19365101 | 0.91 | GRIA1 (0.61) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL16508342 | 0.91 | GRIA1 (0.61) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19365102 | 0.91 | GRIA1 (0.61) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19102175 | 0.91 | GRIA1 (0.61) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL21186352 | 0.90 | GRIA1 (0.67) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19372617 | 0.89 | GRIA1 (0.59) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL21186271 | 0.84 | GRIA1 (0.51) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL24048945 | 0.83 | GRIA1 (0.52) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL21907002 | 0.83 | GRIA1 (0.50) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370447-B1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | UNIV MELBOURNE (AU) | 2016-07-27 | — | — | EP | disclosed |
| WO-2010063069-A1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | THE UNIVERSITY OF MELBOURNE (AU) | 2010-06-10 | — | — | WO | disclosed |