SCHEMBL16360502

SCHEMBL16360502

CC(C)c1nc2c(c3c1[C@@H](c1ccc(C(F)(F)F)cn1)OC31CCCC1I)C(O[Si](C)(C)C(C)(C)C)CC(C)(C)C2

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662905 1.00 CETP (0.57) CETP
SCHEMBL16360292 0.92 CETP (0.55) CETP
SCHEMBL662818 0.92 CETP (0.55) CETP
SCHEMBL661665 0.91 CETP (0.54) CETP
SCHEMBL16258274 0.91 CETP (0.54) CETP
SCHEMBL16258414 0.91 CETP (0.54) CETP
SCHEMBL664999 0.91 CETP (0.54) CETP
SCHEMBL662463 0.90 CETP (0.54) CETP
SCHEMBL16258269 0.90 CETP (0.54) CETP
SCHEMBL16258431 0.90 CETP (0.58) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011101424-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-25 WO disclosed