SCHEMBL16360514

SCHEMBL16360514

CC(C)c1nc2c(c(I)c1CO)C(O[Si](C)(C)C(C)(C)C)CC1(CCC1)C2

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 8/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664482 1.00 CETP (0.35) CETP
SCHEMBL663390 0.98 CETP (0.33) CETP
SCHEMBL2300304 0.98 CETP (0.33) CETP
SCHEMBL662062 0.88 CETP (0.35) CETP
SCHEMBL663465 0.88 CETP (0.35) CETP
SCHEMBL664902 0.83 CETP (0.40) CETP
SCHEMBL661360 0.82 CETP (0.35) CETP
SCHEMBL16359993 0.82 CETP (0.35) CETP
SCHEMBL16360229 0.82 CETP (0.37) CETP
SCHEMBL10196418 0.82 CETP (0.37) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011101424-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-25 WO disclosed