SCHEMBL16360559

SCHEMBL16360559

CC1(C)Cc2nc(C3CCOCC3)c3c(c2C(O[Si](C)(C)C(C)(C)C)C1)C1(CCOCC1)O[C@@H]3c1ccc(C(F)(F)F)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL663989 1.00 CETP (0.69) CETP
SCHEMBL664032 0.96 CETP (0.75) CETP
SCHEMBL16258251 0.96 CETP (0.75) CETP
SCHEMBL16258287 0.96 CETP (0.75) CETP
SCHEMBL664199 0.96 CETP (0.75) CETP
SCHEMBL16360553 0.94 CETP (0.59) CETP
SCHEMBL664092 0.94 CETP (0.59) CETP
SCHEMBL16258343 0.92 CETP (0.61) CETP
SCHEMBL664861 0.92 CETP (0.61) CETP
SCHEMBL663974 0.91 CETP (0.73) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011101424-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-25 WO disclosed