Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481319 | 0.89 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL14411817 | 0.89 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL29902915 | 0.89 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL574038 | 0.86 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL29888274 | 0.86 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL3634865 | 0.86 | TSHR (0.55) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL5321161 | 0.86 | TSHR (0.52) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL21373613 | 0.86 | TSHR (0.52) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL27751205 | 0.86 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2CYP3A4ATM | |
| SCHEMBL26133898 | 0.86 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786828-B1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-7932050-B2 | Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2011-04-26 | — | — | US | disclosed |
| US-20100028926-A1 | Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2010-02-04 | — | — | US | disclosed |
| US-7626018-B2 | Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | bioMérieux (FR) | 2009-12-01 | — | — | US | disclosed |
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | BIOMERIEUX (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1786828-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006030119-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | bioMérieux (FR) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | PEPD, CTRL, PREP | TDP1 1131/4885TSHR 1894/4885SMN1; SMN2 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.