⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160899 | 0.78 | — | — | |
| SCHEMBL183475 | 0.78 | — | — | |
| SCHEMBL27769296 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11782854 | 0.76 | KMT2A (0.50) | — | |
| SCHEMBL26907933 | 0.75 | NR4A2 (0.43) | — | |
| SCHEMBL69933 | 0.75 | NR4A2 (0.43) | — | |
| SCHEMBL163619 | 0.75 | — | — | |
| SCHEMBL1171093 | 0.75 | DAO (0.50) | — | |
| SCHEMBL4731439 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL28355104 | 0.73 | NR4A2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-108383838-B | Amide derivative and application thereof in hypertension, hyperlipidemia and atherosclerosis | 浙江药苑生物科技有限公司 | 2020-08-28 | — | — | CN | disclosed |
| US-9856210-B2 | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis | KYOTO UNIVERSITY (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-2611437-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV KYOTO (JP) | 2017-03-29 | — | — | EP | disclosed |
| EP-2315651-B1 | USE OF MEDIATORS IN THE MANUFACTURING OF FIBERBOARDS | UNIV GOETTINGEN GEORG AUGUST (DE) | 2014-02-26 | — | — | EP | disclosed |
| US-20130225642-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-2611437-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029994-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2012-03-08 | — | — | WO | disclosed |
| US-20110118458-A1 | USE OF MEDIATORS IN THE PRODUCTION OF FIBERBOARDS | GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS (DE) | 2011-05-19 | — | — | US | disclosed |
| EP-2315651-A2 | USE OF MEDIATORS IN THE PRODUCTION OF FIBREBOARD | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (DE) | 2011-05-04 | — | — | EP | disclosed |
| US-20060122232-A1 | 4-Hydroxyfuroic acid derivatives | DEVELOPMENT CENTER FOR BIOTECHNOLOGY | 2006-06-08 | — | — | US | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| US-6596760-B1 | Substituted 4-hydroxy-2-furoic acids are obtained by the fermentation of an asterriquinone, which is a natural product having a 2,5-dioxy-3,6-bis(indolyl)quinone structure. The compounds modulate insulin receptor tyrosine kinase activity | MERCK & CO. INC. | 2003-07-22 | — | — | US | disclosed |
| US-6596760-B1 | Substituted 4-hydroxy-2-furoic acids are obtained by the fermentation of an asterriquinone, which is a natural product having a 2,5-dioxy-3,6-bis(indolyl)quinone structure. The compounds modulate insulin receptor tyrosine kinase activity | MERCK & CO. INC. | 2003-07-22 | — | — | US | disclosed |
| US-6596760-B1 | Substituted 4-hydroxy-2-furoic acids are obtained by the fermentation of an asterriquinone, which is a natural product having a 2,5-dioxy-3,6-bis(indolyl)quinone structure. The compounds modulate insulin receptor tyrosine kinase activity | MERCK & CO. INC. | 2003-07-22 | — | — | US | disclosed |
| US-20030134890-A1 | Antidiabetic 4-hydroxy-2-furoic acids | MERCK & CO., INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030134890-A1 | Antidiabetic 4-hydroxy-2-furoic acids | MERCK & CO., INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030134890-A1 | Antidiabetic 4-hydroxy-2-furoic acids | MERCK & CO., INC. | 2003-07-17 | — | — | US | disclosed |