Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 19/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324232 | 1.00 | FASN (0.68) | FASNMAPK14 | |
| SCHEMBL16365757 | 0.93 | FASN (0.68) | FASN | |
| SCHEMBL16324411 | 0.93 | FASN (0.68) | FASN | |
| SCHEMBL18924558 | 0.93 | FASN (0.68) | FASN | |
| SCHEMBL17739730 | 0.93 | FASN (0.68) | FASN | |
| SCHEMBL16323223 | 0.89 | FASN (0.83) | FASNMAPK14 | |
| SCHEMBL16324462 | 0.88 | FASN (0.63) | FASN | |
| SCHEMBL16365086 | 0.85 | FASN (0.65) | FASN | |
| SCHEMBL16323494 | 0.85 | FASN (0.65) | FASN | |
| SCHEMBL16323722 | 0.84 | FASN (0.63) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014202168-A1 | 1,3-DIAMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-12-24 | — | — | WO | disclosed |