Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174163 | 0.97 | HPGD (0.51) | HPGDPDK2LMNATP53POLB | |
| SCHEMBL16366599 | 0.94 | PDK2 (0.46) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL9916964 | 0.94 | PDK2 (0.46) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL16366511 | 0.94 | PDK2 (0.46) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL15713473 | 0.94 | PDK2 (0.46) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL16366512 | 0.93 | PDK2 (0.48) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL9916951 | 0.93 | PDK2 (0.48) | HPGDPDK2LMNAMAPTAPP | |
| SCHEMBL9916948 | 0.93 | PDK2 (0.43) | PDK2LMNAMAPTAPPNPSR1 | |
| SCHEMBL13486731 | 0.91 | PDK2 (0.48) | HPGDPDK2LMNATP53POLB | |
| SCHEMBL15030815 | 0.91 | PDK2 (0.48) | HPGDPDK2LMNAMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2816025-A1 | AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE | Idemitsu Kosan Co., Ltd (JP) | 2014-12-24 | — | — | EP | disclosed |