Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.68 |
| ▸ | RET | P07949 | 2/20 | 0.68 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.68 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.68 |
| ▸ | CIT | O14578 | 1/20 | 0.68 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.68 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.68 |
| ▸ | STK10 | O94804 | 1/20 | 0.68 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.68 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | RAF1 | P04049 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | FYN | P06241 | 1/20 | 0.68 |
| ▸ | CSF1R | P07333 | 1/20 | 0.68 |
| ▸ | YES1 | P07947 | 1/20 | 0.68 |
| ▸ | LYN | P07948 | 1/20 | 0.68 |
| ▸ | HCK | P08631 | 1/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.68 |
| ▸ | FGR | P09769 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140722 | 0.90 | KDR (0.69) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL3154877 | 0.89 | KDR (0.65) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL449576 | 0.89 | KDR (0.67) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL448015 | 0.88 | KDR (0.64) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL3151027 | 0.87 | KDR (0.65) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL20386826 | 0.85 | KDR (0.62) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL448970 | 0.85 | KDR (0.62) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL427642 | 0.84 | KDR (0.64) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL3146824 | 0.84 | KDR (0.65) | KDRRETMAP3K20RIPK3CIT | |
| SCHEMBL13417724 | 0.84 | KDR (0.61) | KDRRETMAP3K20RIPK3CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |