SCHEMBL1636734

SCHEMBL1636734

CC(=O)OCC(Cl)CCCl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 6/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
USP2 O75604 3/20 0.33
CYP3A4 P08684 3/20 0.33
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4279785 0.84 TDP1 (0.46) TDP1ALDH1A1LMNAHSD17B10USP2
SCHEMBL202653 0.82
SCHEMBL7816892 0.80 TDP1 (0.41) TDP1ALDH1A1LMNAHSD17B10CNR1
SCHEMBL28994092 0.78 TDP1 (0.39) TDP1ALDH1A1LMNAHSD17B10CNR1
SCHEMBL4279004 0.77
SCHEMBL10835256 0.77
SCHEMBL28994093 0.75 TDP1 (0.41) TDP1ALDH1A1LMNAHSD17B10CNR1
SCHEMBL2858728 0.74
Trimethylammonium SCHEMBL29171546 0.72 TDP1 (0.38) TDP1ALDH1A1LMNAHSD17B10CNR1
SCHEMBL11404250 0.72 TDP1 (0.38) TDP1ALDH1A1LMNAHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7930924-B2 System for the online measurement of volatile and semi-volatile compounds and use thereof VANCOUVER ISLAND UNIVERSITY (CA) 2011-04-26 US disclosed
US-7579587-B2 Thermally assisted membrane introduction mass spectrometry (MIMS) interface and method of use thereof VANCOUVER ISLAND UNIVERSITY (CA) 2009-08-25 US disclosed
US-20090084157-A1 SYSTEM FOR THE ONLINE MEASUREMENT OF VOLATILE AND SEMI-VOLATILE COMPOUNDS AND USE THEREOF MALASPINA UNIVERSITY-COLLEGE 2009-04-02 US disclosed
US-20070181799-A1 THERMALLY ASSISTED MEMBRANE INTRODUCTION MASS SPECTROMETRY (MIMS) INTERFACE AND METHOD OF USE THEREOF MALASPINA UNIVERSITY-COLLEGE (CA) 2007-08-09 US disclosed
US-4356295-A COORDINATION CATALYSTS MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1982-10-26 US disclosed