Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | ILK | Q13418 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106185 | 0.85 | CHRM4 (0.39) | CHRM4NMT1MCHR1KITPDGFRA | |
| SCHEMBL13106281 | 0.83 | CHRM4 (0.38) | CHRM4NMT1MCHR1ILKKIT | |
| SCHEMBL13106276 | 0.79 | CHRM4 (0.43) | CHRM4NMT1MCHR1KDR | |
| SCHEMBL31601068 | 0.79 | KDR (0.33) | KITPDGFRAKDR | |
| SCHEMBL13106328 | 0.78 | ADORA2A (0.35) | CHRM4NMT1MCHR1KITPDGFRA | |
| SCHEMBL27359790 | 0.77 | — | — | |
| SCHEMBL31211206 | 0.76 | MEN1 (0.41) | NMT1 | |
| SCHEMBL13106187 | 0.75 | CHRM4 (0.41) | CHRM4NMT1MCHR1 | |
| SCHEMBL17348186 | 0.74 | ADORA2A (0.41) | CHRM4MCHR1KITPDGFRAKDR | |
| SCHEMBL16898837 | 0.72 | MAPT (0.43) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019487-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-9199963-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-12-01 | — | — | US | disclosed |
| WO-2015005489-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-01-15 | — | — | WO | disclosed |