Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 16/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.52 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542919 | 0.84 | PIK3C3 (0.57) | PIK3C3AAK1PIP5K1CPIK3CA | |
| SCHEMBL4407128 | 0.83 | PIK3C3 (0.62) | PIK3C3 | |
| SCHEMBL16371459 | 0.82 | PIK3C3 (0.59) | PIK3C3AAK1 | |
| SCHEMBL28861346 | 0.81 | CYP17A1 (0.55) | PIK3C3AAK1 | |
| SCHEMBL1518824 | 0.79 | PIP5K1C (0.68) | PIK3C3PIP5K1CPIK3CA | |
| SCHEMBL6790193 | 0.79 | PIK3C3 (0.56) | PIK3C3AAK1 | |
| SCHEMBL17872892 | 0.78 | EGFR (0.69) | PIK3C3CNR1PIP5K1CPIK3CA | |
| SCHEMBL16371957 | 0.78 | CIT (0.73) | AAK1 | |
| SCHEMBL16371961 | 0.78 | CIT (0.73) | AAK1 | |
| SCHEMBL6526162 | 0.77 | CNR1 (0.51) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019475-A1 | ARYL AMIDE KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015006100-A1 | ARYL AMIDE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-15 | — | — | WO | disclosed |