Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 17/20 | 0.70 |
| ▸ | ACHE | P22303 | 4/20 | 0.66 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8739172 | 0.83 | BCHE (0.76) | BCHEACHENOX1 | |
| SCHEMBL30300504 | 0.81 | BCHE (0.73) | BCHEACHENOX1 | |
| SCHEMBL4446747 | 0.81 | BCHE (0.73) | BCHEACHENOX1 | |
| SCHEMBL30882096 | 0.79 | BCHE (0.70) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL341905 | 0.79 | NOX1 (1.00) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL522271 | 0.79 | BCHE (0.70) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL30743852 | 0.79 | BCHE (0.70) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL4778133 | 0.79 | BCHE (0.70) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL30198410 | 0.79 | NOX1 (1.00) | BCHEACHENOX1GAAMAPT | |
| SCHEMBL4776664 | 0.79 | BCHE (1.00) | BCHEACHENOX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2966078-A2 | Inhibitors of histone deacetylase | MethylGene Inc. (CA) | 2016-01-13 | — | — | EP | disclosed |
| EP-2343286-B1 | Dibenzo[b,f][1,4]oxazepine derivatives as inhibitors of histone deacetylase | METHYLGENE INC (CA) | 2014-12-31 | — | — | EP | disclosed |